| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1017006 |
| landingPage: |
http://www.iedb.org/assay/1701287 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
1985
|
| study type: | b cell assays |
| subject species: | Tetronarce californica |
| fullName: |
V A Lennon
D J McCormick
E H Lambert
G E Griesmann
M Z Atassi
|
| method: |
radio immuno assay (RIA)
|
| name: |
Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies.
|
| description: |
The peptide was synthesized with a disulfide-bridge between Cys residues at positions 4 and 18.
Sera from rats immunized with the epitope bound AcChoR from innervated and denervated rat muscle as measured by radioimmunoassay and antibody competition assay.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |