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identifier: 1701287
description:
epitope description:KSYCEIIVTHFPFDQQNCTMKLG
antigen name:Acetylcholine receptor subunit alpha
host organism:Rattus norvegicus Lewis
aggregation:
instance of dataset
availability:
available
primaryPublications: 3878521
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017006
landingPage: http://www.iedb.org/assay/1701287
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1985
study type: b cell assays
subject species: Tetronarce californica
fullName:
V A Lennon
D J McCormick
E H Lambert
G E Griesmann
M Z Atassi
method:
radio immuno assay (RIA)
name:
Region of peptide 125-147 of acetylcholine receptor alpha subunit is exposed at neuromuscular junction and induces experimental autoimmune myasthenia gravis, T-cell immunity, and modulating autoantibodies.
description:
The peptide was synthesized with a disulfide-bridge between Cys residues at positions 4 and 18.
Sera from rats immunized with the epitope bound AcChoR from innervated and denervated rat muscle as measured by radioimmunoassay and antibody competition assay.

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