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Title: The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes.
identifier: 1701787
description:
epitope description:DQDLSKKHGQ
antigen name:Calmodulin-sensitive adenylate cyclase
host organism:Mus musculus A/J
aggregation:
instance of dataset
availability:
available
primaryPublications: 19720758
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1018500
landingPage: http://www.iedb.org/assay/1701787
type:
Literature
publicationVenue:
Infect Immun
dates:
2009
study type: b cell assays
subject species: Bacillus anthracis
fullName:
Melissa L Nguyen
Simon Terzyan
Jimmy D Ballard
Judith A James
A Darise Farris
method:
ELISA
name:
The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes.
description:
This peptide is not significantly reactive with unfractionated EF antisera, but it was reactive with a fraction enriched on Lethal factor reactivity, implying its recognition is by antibodies cross-reactive with LF. However, this cross-reactive fraction of EF antisera is unable to neutralize either EF or LF.

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