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Title: Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit.
identifier: 1701354
description:
epitope description:MKRPSREKQDKKIFTEDID
antigen name:Acetylcholine receptor subunit alpha (UniProt:P02708)
host organism:Rattus norvegicus Lewis
antibody name:149
aggregation:
instance of dataset
availability:
available
primaryPublications: 3362855
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1010102
landingPage: http://www.iedb.org/assay/1701354
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1988
study type: b cell assays
subject species: Homo sapiens
fullName:
S J Tzartos
A Kokla
S L Walgrave
B M Conti-Tronconi
method:
radio immuno assay (RIA)
name:
Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit.
description:
MAb 149 reacted predominantly with the epitope, but also reacted weakly with other AChR peptides, including P22 (SPLIKHPEVKSAIEGIK) and P1 (SEHETRLVAKLFKD) in a study of overlapping peptides. Previous published results proposed the epitope to be residues 339-346.

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