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Title: High-resolution epitope mapping and fine antigenic characterization of the main immunogenic region of the acetylcholine receptor. Improving the binding activity of synthetic analogues of the region.
identifier: 1704172
description:
epitope description:WNPDD
antigen name:Acetylcholine receptor subunit alpha (UniProt:P02708)
host organism:Rattus norvegicus Lewis
antibody name:mAb 6
aggregation:
instance of dataset
availability:
available
primaryPublications: 7678806
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006847
landingPage: http://www.iedb.org/assay/1704172
type:
Literature
publicationVenue:
Eur J Biochem
dates:
1993
study type: b cell assays
subject species: Homo sapiens
fullName:
I Papadouli
C Sakarellos
S J Tzartos
method:
ELISA
name:
High-resolution epitope mapping and fine antigenic characterization of the main immunogenic region of the acetylcholine receptor. Improving the binding activity of synthetic analogues of the region.
description:
This minimal epitope was mapped from an overlapping peptides study. Peptide analogs with single amino acid substitutions at residue N2, P3 and D5 showed that these are critical residues for mAb binding.

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