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identifier: 1704525
description:
epitope description:VDNARVAVQPERLFSEMKWHLNGLTQPVTLPQDLKEAVE
antigen name:Acetylcholine receptor subunit beta
host organism:Rattus norvegicus Lewis
antibody name:111, 148
aggregation:
instance of dataset
availability:
available
primaryPublications: 2424498
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017004
landingPage: http://www.iedb.org/assay/1704525
type:
Literature
publicationVenue:
Biochemistry
dates:
1986
study type: b cell assays
subject species: Tetronarce californica
fullName:
M Ratnam
P B Sargent
V Sarin
J L Fox
D L Nguyen
J Rivier
M Criado
J Lindstrom
method:
western blot
name:
Location of antigenic determinants on primary sequences of subunits of nicotinic acetylcholine receptor by peptide mapping.
description:
The epitope sequence is from the reference cited: Noda et al. (1983) Nature 302(5908): 528-532 [PMID: 6188060]. The epitope was deduced.
The epitope recognized by the mAbs was deduced based on reactivity with fragments generated by V8 protease or papain digestion of AChR beta subunit.

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