Beta 2-adrenergic receptor antibodies in myasthenia gravis. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Beta 2-adrenergic receptor antibodies in myasthenia gravis.

Dataset

identifier:	1704529
description:	epitope description:HWYRATHQEAINCYANETCCDFFTNQ antigen name:Beta-2 adrenergic receptor host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	1378277

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016975
landingPage:	http://www.iedb.org/assay/1704529

Publication

type:	Literature
publicationVenue:	J Autoimmun
dates:	1992

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	H Eng Y Magnusson G Matell A K Lefvert R Saponja J Hoebeke

Data Type

method:	immunoprecipitation

Study

name:	Beta 2-adrenergic receptor antibodies in myasthenia gravis.
description:	Affinity-purified antibody to the epitope was able to bind to Adrenergic beta-2- receptor extracted from transfected E. coli membranes in a Western blot. Binding to the epitope was also shown by immunoprecipitation. Affinity purified antibody competed for receptor binding with beta antagonist iodo-cyanopindolol.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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