Differential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigens.

Title:

Dataset

identifier:	1704779
description:	epitope description:VKMTLKNREPVQLET antigen name:Small nuclear ribonucleoprotein Sm D1 host organism:Mus musculus HLA-DR4 Tg
aggregation:	instance of dataset
availability:	available
primaryPublications:	20007529

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017698
landingPage:	http://www.iedb.org/assay/1704779

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2010

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Chao Jiang Umesh S Deshmukh Felicia Gaskin Harini Bagavant Julie Hanson Chella S David Shu Man Fu

Data Type

method:	ELISA

Study

name:	Differential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigens.
description:	The epitope sequence was found in the cited reference Deshmukh et al. J Immunol. 2007 Feb 15 178(4):2565-71 [PMID: 17277166]. All mice strains tested produced the same outcome.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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