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Title: Anti-peptide antibodies against an autoimmune epitope on human muscarinic receptor mimic functional autoantibodies against the same epitope in patients with idiopathic dilated cardiomyopathy.
identifier: 1702300
description:
epitope description:VRTVEDGECYIQFFSNAAVTFGTAI
antigen name:Muscarinic acetylcholine receptor M2
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 8682112
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017015
landingPage: http://www.iedb.org/assay/1702300
type:
Literature
publicationVenue:
Eur Heart J
dates:
1995
study type: b cell assays
subject species: Homo sapiens
fullName:
M L Fu
method:
biological activity
name:
Anti-peptide antibodies against an autoimmune epitope on human muscarinic receptor mimic functional autoantibodies against the same epitope in patients with idiopathic dilated cardiomyopathy.
description:
Administration of the Ab inhibited both the maximal rate of rise of ventricular pressure and heart rate, suggesting that the Ab was able to exert both negative chronotropic and inotropic effects in vivo.

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