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Title: Antigenic role of single residues within the main immunogenic region of the nicotinic acetylcholine receptor.
identifier: 1702364
description:
epitope description:WNPADYGGIK
antigen name:Acetylcholine receptor subunit alpha
host organism:Rattus norvegicus Lewis
antibody name:6, 50, 47, 22
aggregation:
instance of dataset
availability:
available
primaryPublications: 1695844
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016992
landingPage: http://www.iedb.org/assay/1702364
type:
Literature
publicationVenue:
Biochem J
dates:
1990
study type: b cell assays
subject species: Tetronarce californica
fullName:
I Papadouli
S Potamianos
I Hadjidakis
E Bairaktari
V Tsikaris
C Sakarellos
M T Cung
M Marraud
S J Tzartos
method:
antigen inhibition
name:
Antigenic role of single residues within the main immunogenic region of the nicotinic acetylcholine receptor.
description:
Mutational analysis revealed that residues N2, P3, D5 were critical for binding. Similar results were observed using direct binding experiments with substituted peptides. Mutations G7A and K10A increased binding.

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