Definition of myasthenogenic sites of the human acetylcholine receptor using synthetic peptides. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Definition of myasthenogenic sites of the human acetylcholine receptor using synthetic peptides.

Dataset

identifier:	1702945
description:	epitope description:KSYCEIIVTHFPFDEQNCSMKLG + NLeu(M20) antigen name:Acetylcholine receptor subunit alpha (UniProt:P02708) host organism:Rattus norvegicus Lewis
aggregation:	instance of dataset
availability:	available
primaryPublications:	2446556

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017001
landingPage:	http://www.iedb.org/assay/1702945

Publication

type:	Literature
publicationVenue:	Ann N Y Acad Sci
dates:	1987

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	V A Lennon G A Griesmann D J McCormick Z X Huang H Feng E H Lambert

Data Type

method:	ELISA

Study

name:	Definition of myasthenogenic sites of the human acetylcholine receptor using synthetic peptides.
description:	For the assay antigen, similar results were observed with a C4S substitution that eliminated a disulfide bond. Similar results were observed with a mAb raised against the Talpha125-147 peptide.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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