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Title: Conformational modification enhances myasthenogenicity in synthetic peptide of acetylcholine receptor alpha-subunit.
identifier: 1703869
description:
epitope description:YTCCPD
antigen name:Acetylcholine receptor subunit alpha
host organism:Rattus norvegicus Lewis
aggregation:
instance of dataset
availability:
available
primaryPublications: 2086725
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016991
landingPage: http://www.iedb.org/assay/1703869
type:
Literature
publicationVenue:
J Neurol Sci
dates:
1990
study type: b cell assays
subject species: Tetronarce californica
fullName:
M Takamori
S Okumura
K Komai
R Satake
method:
radio immuno assay (RIA)
name:
Conformational modification enhances myasthenogenicity in synthetic peptide of acetylcholine receptor alpha-subunit.
description:
Immunization of rats with the epitope elicited antibodies to intact acetylcholine receptor (AChR). Sera also blocked the binding of AChR to bungarotoxin. When the epitope was administered as a conjugate peptide (107-116-NPGG-190-195) reactivity to the corresponding epitope was significantly greater.

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