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identifier: 1705158
description:
epitope description:KLLLDYTGKINPGGYTCCPD
host organism:Rattus norvegicus Lewis
aggregation:
instance of dataset
availability:
available
primaryPublications: 2086725
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016991
landingPage: http://www.iedb.org/assay/1705158
type:
Literature
publicationVenue:
J Neurol Sci
dates:
1990
study type: b cell assays
subject species:
fullName:
M Takamori
S Okumura
K Komai
R Satake
method:
radio immuno assay (RIA)
name:
Conformational modification enhances myasthenogenicity in synthetic peptide of acetylcholine receptor alpha-subunit.
description:
The epitope is comprised of two peptide sequences (107-116 and 190-195) from the alpha subunit of T. californica AChR conjugated through a NPGG linker.
When the epitope was administered as a conjugate peptide (107-116-NPGG-190-195) reactivity to the corresponding AChR was greater than the cognate peptides alone or in combination without the linker.

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