| Title: | Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1017066 |
| landingPage: |
http://www.iedb.org/assay/1708868 |
| type: |
Literature
|
| publicationVenue: |
Science
|
| dates: |
1989
|
| study type: | b cell assays |
| subject species: | Mus musculus |
| fullName: |
S E Millar
S M Chamow
A W Baur
C Oliver
F Robey
J Dean
|
| method: |
protection from fertility
|
| name: |
Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice.
|
| description: |
In nine mice immunized with the epitope a contraceptive effect was observed that lasted from 16 to 36 weeks. At the time of birth of their first litters, the titer of antibodies to ZP3 had dropped to below that of control animals, indicating that there is a correlation between antibody concentration and fertility.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |