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identifier: 1708868
description:
epitope description:CSNSSSSQFQIHGPRQ
antigen name:Zona pellucida sperm-binding protein 3
host organism:Mus musculus Swiss
aggregation:
instance of dataset
availability:
available
primaryPublications: 2479101
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017066
landingPage: http://www.iedb.org/assay/1708868
type:
Literature
publicationVenue:
Science
dates:
1989
study type: b cell assays
subject species: Mus musculus
fullName:
S E Millar
S M Chamow
A W Baur
C Oliver
F Robey
J Dean
method:
protection from fertility
name:
Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice.
description:
In nine mice immunized with the epitope a contraceptive effect was observed that lasted from 16 to 36 weeks. At the time of birth of their first litters, the titer of antibodies to ZP3 had dropped to below that of control animals, indicating that there is a correlation between antibody concentration and fertility.

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