The tyrosine phosphorylation site of the acetylcholine receptor beta subunit is located in a highly immunogenic epitope implicated in channel function: antibody probes for beta subunit phosphorylation and function.

Title:

Dataset

identifier:	1711925
description:	epitope description:RGTDEYFIRKPP antigen name:Acetylcholine receptor subunit beta host organism:Rattus norvegicus Lewis antibody name:148, 151, 120
aggregation:	instance of dataset
availability:	available
primaryPublications:	7505221

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1016960
landingPage:	http://www.iedb.org/assay/1711925

Publication

type:	Literature
publicationVenue:	EMBO J
dates:	1993

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	S J Tzartos C Valcana R Kouvatsou A Kokla

Data Type

method:	ELISA

Study

name:	The tyrosine phosphorylation site of the acetylcholine receptor beta subunit is located in a highly immunogenic epitope implicated in channel function: antibody probes for beta subunit phosphorylation and function.
description:	The epitope was deduced by testing overlapping peptides. The epitope-specific mAb(s) recognized the AChR peptide by ELISA. MAbs 120 and 151 were of IgG1 isotype, while mAb 148 was of IgG2 isotype.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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