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Title: Prokaryotic expression of the thyrotropin receptor and identification of an immunogenic region of the protein using synthetic peptides.
identifier: 1710620
description:
epitope description:EEQEDEIIGFGQELKN
antigen name:Thyrotropin receptor
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 1883361
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017347
landingPage: http://www.iedb.org/assay/1710620
type:
Literature
publicationVenue:
Biochem Biophys Res Commun
dates:
1991
study type: b cell assays
subject species: Homo sapiens
fullName:
O
R K Desai
G S Seetharamaiah
C A Jones
G P Allaway
T Akamizu
L D Kohn
B S Prabhakar
method:
ELISA
name:
Prokaryotic expression of the thyrotropin receptor and identification of an immunogenic region of the protein using synthetic peptides.
description:
The epitope sequence is identical in thyroid stimulating hormone receptor from human and rat.
One of 29 sera from Graves' disease patients weakly bound the epitope at a level greater than the mean +/- 2 SD of the sera from normal subjects, but overall there was no significant difference between the Graves' disease patients and normal controls.

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