Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1714925 |
| description: |
epitope description:E101, G105, S106, D107, T110, G111, E112, P113, S114, H125, P152, S153, Q154, P155, W156, R158, L159
antigen name:Interleukin-23 subunit alpha
host organism:Mus musculus
antibody name:chimeric 7G10
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
18708069 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1013330 |
| landingPage: |
http://www.iedb.org/assay/1714925 |
| type: |
Literature
|
| publicationVenue: |
J Mol Biol
|
| dates: |
2008
|
| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
Brian M Beyer
Richard Ingram
Lata Ramanathan
Paul Reichert
Hung V Le
Vincent Madison
Peter Orth
|
| method: |
x-ray crystallography
|
| name: |
Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody.
|
| description: |
Epitope was calculated from the structure [PDB: 3D85].
The epitope of Fab 7G10 on human interleukin-23 p19 was determined from the crystal structure of the complex, determined using the molecular replacement approach.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
