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Title: Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment.
identifier: 1716643
description:
epitope description:EFRH
antigen name:Amyloid beta A4 protein
host organism:Mus musculus
antibody name:WO-2
aggregation:
instance of dataset
availability:
available
primaryPublications: 20014445
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019026
landingPage: http://www.iedb.org/assay/1716643
type:
Literature
publicationVenue:
Protein Sci
dates:
2010
study type: b cell assays
subject species: Homo sapiens
fullName:
Remy Robert
Victor A Streltsov
Janet Newman
Lesley A Pearce
Kim L Wark
Olan Dolezal
method:
surface plasmon resonance (SPR)
name:
Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment.
description:
The humanized epitope-specific mAb had a KD of 6.15 nM.

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