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Title: Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
identifier: 1713294
description:
epitope description:T62, K64, R86, Y88, R115, F136, G138, F140
antigen name:Thyrotropin receptor
host organism:Mus musculus
antibody name:1H7
aggregation:
instance of dataset
availability:
available
primaryPublications: 15319453
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017300
landingPage: http://www.iedb.org/assay/1713294
type:
Literature
publicationVenue:
Mol Endocrinol
dates:
2004
study type: b cell assays
subject species: Homo sapiens
fullName:
Sabine Costagliola
Marco Bonomi
Nils G Morgenthaler
Joost Van Durme
Valé
rie Panneels
Samuel Refetoff
Gilbert Vassart
method:
flow cytometry
name:
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
description:
MAb 1H7, which recognizes the epitopic residues, bound to mouse TSHR expressed on a Chinese hamster ovary cell line MT3.

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