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Title: Identification of antigenic epitopes of 1D antigen recognized by antibodies in the serum of patients with thyroid-associated ophthalmopathy.
identifier: 1714652
description:
epitope description:RGRDASKKALGPRRNSDLGKEPKRGGLKKSFSRDRDE
antigen name:Leiomodin-1
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 7586727
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017383
landingPage: http://www.iedb.org/assay/1714652
type:
Literature
publicationVenue:
Clin Immunol Immunopathol
dates:
1995
study type: b cell assays
subject species: Homo sapiens
fullName:
Z G Zhang
J R Wall
N F Bernard
method:
western blot
name:
Identification of antigenic epitopes of 1D antigen recognized by antibodies in the serum of patients with thyroid-associated ophthalmopathy.
description:
The epitope sequence is from the reference cited: Dong et al. (1991) Clin Endocrinol Metab 72: 1375-1381 [PMID: 2026759].
Sera from 3 of 15 TAO patients recognized the epitope expressed as a fusion protein. Four peptides, including the epitope, were selected from a random fragment cDNA library of 1D using a pool of sera from 4 patients with TAO.

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