Monoclonal antibodies to the human TSH receptor: epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells.

Title:

Monoclonal antibodies to the human TSH receptor: epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells.

Dataset

identifier:	1714810
description:	epitope description:SDEFNPCEDIMGYK antigen name:Thyrotropin receptor host organism:Mus musculus C57BL/6 antibody name:A7
aggregation:	instance of dataset
availability:	available
primaryPublications:	9156519

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1018496
landingPage:	http://www.iedb.org/assay/1714810

Publication

type:	Literature
publicationVenue:	J Mol Endocrinol
dates:	1996

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	L B Nicholson H Vlase P Graves M Nilsson J Molne G C Huang N G Morgenthaler T F Davies A M McGregor J P Banga

Data Type

method:	ELISA

Study

name:	Monoclonal antibodies to the human TSH receptor: epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells.
description:	The epitope sequence was cited in Libert et al. Biochem Biophys Res Commun. 1989 Dec 29 165(3):1250-5 [PMID: 2610690]. The epitope-specific mAb recognized the peptide in ELISA and Western blot. The epitope sequence was deduced by study of truncated TSH-R constructs.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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