Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector.

Title:

Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector.

Dataset

identifier:	1717036
description:	epitope description:DNTGLTRVPMDAFQVGKFPEDFESCD antigen name:Thyroid peroxidase (UniProt:P07202) host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	1716261

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1018491
landingPage:	http://www.iedb.org/assay/1717036

Publication

type:	Literature
publicationVenue:	J Clin Endocrinol Metab
dates:	1991

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	F Libert M Ludgate C Dinsart G Vassart

Data Type

method:	phage display

Study

name:	Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector.
description:	The vector pUEX1 was used to clone and express small random fragments of TPO cDNA in E. coli as a beta-galactosidase fusion protein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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