A region on the human thyrotropin receptor which can induce antibodies that inhibit thyrotropin-mediated activation of in vitro thyroid cell function also contains a highly immunogenic epitope.

Title:

A region on the human thyrotropin receptor which can induce antibodies that inhibit thyrotropin-mediated activation of in vitro thyroid cell function also contains a highly immunogenic epitope.

Dataset

identifier:	1735752
description:	epitope description:GYKEKSKFQDTHNNA antigen name:Thyrotropin receptor host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	7980849

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017345
landingPage:	http://www.iedb.org/assay/1735752

Publication

type:	Literature
publicationVenue:	J Autoimmun
dates:	1994

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	J S Dallas G S Seetharamaiah S J Cunningham R M Goldblum R K Desai B S Prabhakar

Data Type

method:	antigen inhibition

Study

name:	A region on the human thyrotropin receptor which can induce antibodies that inhibit thyrotropin-mediated activation of in vitro thyroid cell function also contains a highly immunogenic epitope.
description:	Recombinant ETSHr competed with the epitope for binding by sera raised to the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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