Inhibition of PDC-E2 human combinatorial autoantibodies by peptide mimotopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Inhibition of PDC-E2 human combinatorial autoantibodies by peptide mimotopes.

Dataset

identifier:	1755281
description:	epitope description:WMSYPDRTLRTS host organism:Homo sapiens antibody name:SP1, SP4
aggregation:	instance of dataset
availability:	available
primaryPublications:	9115581

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017226
landingPage:	http://www.iedb.org/assay/1755281

Publication

type:	Literature
publicationVenue:	J Autoimmun
dates:	1996

Dimension

study type:	b cell assays
subject species:

Person

fullName:	P S Leung S Cha R E Joplin C Galperin J Van de Water A A Ansari R L Coppel P J Schatz S Cwirla L E Fabris J M Neuberger M E Gershwin

Data Type

method:	antigen inhibition

Study

name:	Inhibition of PDC-E2 human combinatorial autoantibodies by peptide mimotopes.
description:	The epitope inhibited binding of the autoantibodies to biliary epithelial cells from patients with primary biliary cirrhosis. A single amino acid substitution at position 2 from Met to Glu gave only a minimal reduction in staining.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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