| Title: | A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1011158 |
| landingPage: |
http://www.iedb.org/assay/1761510 |
| type: |
Literature
|
| publicationVenue: |
Biol Reprod
|
| dates: |
1999
|
| study type: | b cell assays |
| subject species: | Mus musculus |
| fullName: |
W Sun
Y H Lou
J Dean
K S Tung
|
| method: |
immuno staining
|
| name: |
A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida.
|
| description: |
Of the chimeric peptides that contained RNase and ZP2, RNase-ZP2 elicited ZP antibody whereas ZP2-RNase did not. In contrast, both chimeric peptides containing the malaria epitope and ZP2 induced ZP antibody, although the titers were consistently below the titer induced by the RNase-ZP2 chimeric peptide. The response to the ZP2 chimeric peptide was confined to mice of the H-2k and H-2b haplotypes (A/J, B6, B6AF1 and C3H).
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |