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identifier: 1761510
description:
epitope description:TDVRYKD
antigen name:Zona pellucida sperm-binding protein 2
host organism:Mus musculus (C57BL/6 X A/J)
aggregation:
instance of dataset
availability:
available
primaryPublications: 10084964
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1011158
landingPage: http://www.iedb.org/assay/1761510
type:
Literature
publicationVenue:
Biol Reprod
dates:
1999
study type: b cell assays
subject species: Mus musculus
fullName:
W Sun
Y H Lou
J Dean
K S Tung
method:
immuno staining
name:
A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida.
description:
Of the chimeric peptides that contained RNase and ZP2, RNase-ZP2 elicited ZP antibody whereas ZP2-RNase did not. In contrast, both chimeric peptides containing the malaria epitope and ZP2 induced ZP antibody, although the titers were consistently below the titer induced by the RNase-ZP2 chimeric peptide. The response to the ZP2 chimeric peptide was confined to mice of the H-2k and H-2b haplotypes (A/J, B6, B6AF1 and C3H).

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