Defining the major antibody epitopes on the human thyrotropin receptor in immunized mice: evidence for intramolecular epitope spreading.

Title:

Defining the major antibody epitopes on the human thyrotropin receptor in immunized mice: evidence for intramolecular epitope spreading.

identifier:	1764334
description:	epitope description:FRVTCKDIQRIPSLPPSTQT antigen name:Thyrotropin receptor host organism:Mus musculus CBA/J
aggregation:	instance of dataset
availability:	available
primaryPublications:	7664661

study type:	b cell assays
subject species:	Homo sapiens

fullName:	H Vlase M Nakashima P N Graves Y J C Morris T F Davies

method:	ELISA

name:	Defining the major antibody epitopes on the human thyrotropin receptor in immunized mice: evidence for intramolecular epitope spreading.
description:	The epitope sequence was cited in Libert et al. Biochem Biophys Res Commun. 1989 Dec 29 165(3):1250-5 [PMID: 2610690]. One booster injection was not sufficient to induce anti-epitope antibodies. Antisera from Balb/c mice boosted once with the peitope did not recognize the epitope.

name:	iedb
homePage:	http://www.iedb.org

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