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Title: Design and delivery of a cryptic PrP(C) epitope for induction of PrP(Sc)-specific antibody responses.
identifier: 1764131
description:
epitope description:QVYYRPVDQYSNQN
antigen name:Major prion protein
host organism:Ovis aries
antibody name:cerebral spinal fluid
aggregation:
instance of dataset
availability:
available
primaryPublications: 19925901
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019267
landingPage: http://www.iedb.org/assay/1764131
type:
Literature
publicationVenue:
Vaccine
dates:
2010
study type: b cell assays
subject species: Ovis aries
fullName:
Peter D Hedlin
Neil R Cashman
Li Li
Jyotsana Gupta
Lorne A Babiuk
Andrew A Potter
Philip Griebel
Scott Napper
method:
ELISA
name:
Design and delivery of a cryptic PrP(C) epitope for induction of PrP(Sc)-specific antibody responses.
description:
Antibodies generated using the beta2(2+YYR+9)I construct were demonstrated in cerebral spinal fluid (CSF). Regression analysis confirmed significant correlation between titers in serum and those in CSF.

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