Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication.
identifier: 1764795
description:
epitope description:K122, T123, A159, K160
antigen name:Large envelope protein
host organism:Mus musculus
antibody name:S1, 2C8, D12, 1C10
aggregation:
instance of dataset
availability:
available
primaryPublications: 19812261
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019143
landingPage: http://www.iedb.org/assay/1764795
type:
Literature
publicationVenue:
J Gen Virol
dates:
2010
study type: b cell assays
subject species: Hepatitis B virus subtype adw2
fullName:
Chunchen Wu
Xiaoyong Zhang
Yongjun Tian
Jianhua Song
Dongliang Yang
Michael Roggendorf
Mengji Lu
Xinwen Chen
method:
ELISA
name:
Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication.
description:
The epitope-specific mAbs recognized wild-type HBsAg by ELISA and immunostaining. Mutations of the epitopic residues resulted in impaired or reduced antibody binding.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston