Immunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.

Title:

Immunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.

Dataset

identifier:	1796738
description:	epitope description:AECDWGKGGRWRLWPGASGKTEACGP host organism:Mus musculus APPswe/PSEN1
aggregation:	instance of dataset
availability:	available
primaryPublications:	20493257

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020941
landingPage:	http://www.iedb.org/assay/1796738

Publication

type:	Literature
publicationVenue:	Neurobiol Dis
dates:	2010

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Chiou-Miin Wang Sarah Devries Marybeth Camboni Matthew Glass Paul T Martin

Data Type

method:	ELISA

Study

name:	Immunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.
description:	Sera from epitope-immunized APPswe/PSEN1 mice contained high level of Aß1-42-specific Ab.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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