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Title: New insights into the conformational dominant epitopes on thyroid peroxidase recognized by human autoantibodies.
identifier: 1796949
description:
epitope description:GLPRLETPADLSTAIASRS
antigen name:Thyroid peroxidase (UniProt:P07202)
host organism:Mus musculus BALB/c
antibody name:Mouse mAb 15, 18, 64
aggregation:
instance of dataset
availability:
available
primaryPublications: 15761037
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1017355
landingPage: http://www.iedb.org/assay/1796949
type:
Literature
publicationVenue:
Endocrinology
dates:
2005
study type: b cell assays
subject species: Homo sapiens
fullName:
Damien Bresson
Sandra A Rebuffat
Brigitte Nguyen
J Paul Banga
Andrzej Gardas
Sylvie Peraldi-Roux
method:
cross blocking
name:
New insights into the conformational dominant epitopes on thyroid peroxidase recognized by human autoantibodies.
description:
The epitope specific rabbit anti-P14 serum inhibited binding of mouse mAbs 15, 18, 64 to thyroid peroxidase (TPO) by 72%, 65% and 54% respectively. The mAbs recognized a conformational dominant epitope region IDR/A.

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