Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1796998 |
| description: |
epitope description:L-glycero-alpha-D-manno-Hepp-(1->2)-L-glycero-alpha-D-manno-Hepp-(1->3)-L-glycero-alpha-D-manno-Hepp-(1->5)-alpha-Kdo
antigen name:lipooligosaccharide
host organism:Mus musculus BALB/c
antibody name:MAHI3
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
7543887 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1009944 |
| landingPage: |
http://www.iedb.org/assay/1796998 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
1995
|
| study type: | b cell assays |
| subject species: | Haemophilus influenzae |
| fullName: |
S Borrelli
O Hegedus
D H Shaw
P E Jansson
A A Lindberg
|
| method: |
ELISA
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| name: |
The tetrasaccharide L-alpha-D-heptose1-->2-L-alpha-D-heptose1--> 3-L-alpha-D-heptose1-->(3-deoxy-D-manno-octulosonic acid) and phosphate in lipid A define the conserved epitope in Haemophilus lipopolysaccharides recognized by a monoclonal antibody.
|
2-L-alpha-D-heptose1--> 3-L-alpha-D-heptose1-->(3-deoxy-D-manno-octulosonic acid) and phosphate in lipid A define the conserved epitope in Haemophilus lipopolysaccharides recognized by a monoclonal antibody.-->
| description: |
The epitope is deduced. The phosphates of the lipid A moiety of LOS are also important for the definition of the epitope as the substrate for the mAb, and therefore this epitope is listed as partial. The epitope is conserved in H. haemophilus and H. ducreyi, among others.
The epitope-specific MAb reacted with all the H. ducreyi strains tested in ELISA and immunoblot, from whole cells and lysates.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
