Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid.

Title:

Dataset

identifier:	1799109
description:	epitope description:N(6)-trifluoroacetyl-L-lysine host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	7519986

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1017239
landingPage:	http://www.iedb.org/assay/1799109

Publication

type:	Literature
publicationVenue:	Eur J Biochem
dates:	1994

Dimension

study type:	b cell assays
subject species:

Person

fullName:	U Christen J Quinn S J Yeaman J G Kenna J B Clarke A J Gandolfi J Gut

Data Type

method:	antigen inhibition

Study

name:	Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid.
description:	The epitope inhibited binding of the epitope-specific antibodies to the lipoylated E2 subunit of rat and human puruvate dehydrogenase.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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