Murine malaria: anti-erythrocytic antibodies recognize N-acetyl neuraminic acid residues. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Murine malaria: anti-erythrocytic antibodies recognize N-acetyl neuraminic acid residues.

Dataset

identifier:	1800806
description:	epitope description:N-acetylneuraminic acid host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	7508418

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003121
landingPage:	http://www.iedb.org/assay/1800806

Publication

type:	Literature
publicationVenue:	Immunology
dates:	1993

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	A K Satapathy M K Das B Ravindran

Data Type

method:	antigen inhibition

Study

name:	Murine malaria: anti-erythrocytic antibodies recognize N-acetyl neuraminic acid residues.
description:	Mice infected with Plasmodium berghei made antibodies to the epitope, as detected by antibody binding to plate-bound infected and non-infected mouse erythrocytes being competed by the epitope. Direct binding was also shown by sera from mice during peak parasite infection. Antibodies affinity-purified on a Fetuin column were found to bind to double and single-stranded DNA.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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