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Title: Identification of outer membrane porin f protein of Yersinia enterocolitica recognized by antithyrotopin receptor antibodies in Graves' disease and determination of its epitope using mass spectrometry and bioinformatics tools.
identifier: 1800999
description:
epitope description:DAFGGVYS
antigen name:Thyrotropin receptor
host organism:Mus musculus
antibody name:anti-hTSHR mAb A9
aggregation:
instance of dataset
availability:
available
primaryPublications: 20484489
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1020987
landingPage: http://www.iedb.org/assay/1800999
type:
Literature
publicationVenue:
J Clin Endocrinol Metab
dates:
2010
study type: b cell assays
subject species: Homo sapiens
fullName:
Zhe Wang
Qunye Zhang
Jing Lu
Fan Jiang
Haiqing Zhang
Ling Gao
Jiajun Zhao
method:
western blot
name:
Identification of outer membrane porin f protein of Yersinia enterocolitica recognized by antithyrotopin receptor antibodies in Graves' disease and determination of its epitope using mass spectrometry and bioinformatics tools.
description:
The epitope was deduced based on reactivity determined by immunoblot analysis. Whereas mAb A9 bound full length human TSHR, it failed to bind the fragment with residues 198-205 deleted.

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