Immunological Data Discovery Index
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identifier: 1802026
description:
epitope description:K310, G328, T329, D330, P332, K361, E362, P364, E384, K385
antigen name:Genome polyprotein
host organism:Mus musculus C57BL/6
antibody name:E106
aggregation:
instance of dataset
availability:
available
primaryPublications: 20369024
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019744
landingPage: http://www.iedb.org/assay/1802026
type:
Literature
publicationVenue:
PLoS Pathog
dates:
2010
study type: b cell assays
subject species: Dengue virus type 1 strain 16007
fullName:
Bimmi Shrestha
James D Brien
Soila Sukupolvi-Petty
S Kyle Austin
Melissa A Edeling
Taekyung Kim
Katie M O'Brien
Christopher A Nelson
Syd Johnson
Daved H Fremont
Michael S Diamond
method:
flow cytometry
name:
The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1.
description:
The epitope specific monoclonal antibody bound DIII displayed on yeast cells. The epitope was deduced through the loss of binding with substitutions at residues K310, G328, T329, D330, P332, K361, E362, P364, E384 and K385.

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