Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells.

Dataset

identifier:	1802696
description:	epitope description:alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group host organism:Mus musculus C57BL/6 alpha1,3GT null
aggregation:	instance of dataset
availability:	available
primaryPublications:	14607944

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020577
landingPage:	http://www.iedb.org/assay/1802696

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2003

Dimension

study type:	b cell assays
subject species:	Oryctolagus cuniculus

Person

fullName:	Toshiyasu Kawahara Hideki Ohdan Guiling Zhao Yong-Guang Yang Megan Sykes

Data Type

method:	ELISA

Study

name:	Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells.
description:	ELISA detection of epitope-specific IgM in μ-/- recipients showed that the spleen and peritoneal cavity B cells transfer generate epitope-specific serum IgM, but the homing of both type of cells to the spleen of the recipient, and its conversion from Mac1+ to Mac1- phenotype is required for the generation of these Abs.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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