Establishment of a mouse IgA nephropathy model with the MBP-20-peptide fusion protein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Establishment of a mouse IgA nephropathy model with the MBP-20-peptide fusion protein.

Dataset

identifier:	1803213
description:	epitope description:NVGGDNVDIHSIVPVGQDPH antigen name:ABC transporter, substrate-binding protein, putative host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	20730864

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1021151
landingPage:	http://www.iedb.org/assay/1803213

Publication

type:	Literature
publicationVenue:	Anat Rec (Hoboken)
dates:	2010

Dimension

study type:	b cell assays
subject species:	Staphylococcus aureus A9635

Person

fullName:	Lei Zhang Fei Ye Yan He Dan Kong Changsong Han Zhijie Zhao Jiang Zhu Hongxue Meng Xinghan Liu Xiaoming Jin

Data Type

method:	in vivo assay

Study

name:	Establishment of a mouse IgA nephropathy model with the MBP-20-peptide fusion protein.
description:	Mice injected with the epitope had increased hematuria and proteinuria as well as pathological deposits as seen by histology and electron microscopy of kidney glomeruli. These mice also had deposition of IgA, IgG and IgM as well as complement in the glomeruli.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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