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identifier: 1803549
description:
epitope description:NSELLSLINDMPITNDQKKLMSNNOC
host organism:Mus musculus BALB/c
antibody name:Motavizumab
aggregation:
instance of dataset
availability:
available
primaryPublications: 20943340
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021210
landingPage: http://www.iedb.org/assay/1803549
type:
Literature
publicationVenue:
J Pharm Biomed Anal
dates:
2011
study type: b cell assays
subject species:
fullName:
James B McGivney 4th
Eric Bishop
Kenneth Miller
Jose Casas-Finet
Harry Yang
Ziping Wei
Robert Strouse
Mark Schenerman
method:
ELISA
name:
Evaluation of a synthetic peptide as a replacement for the recombinant fusion protein of respiratory syncytial virus in a potency ELISA.
description:
The residue at position 25 is an ornithine added for the purpose of coupling.
Motavizumab binding to the candidate peptides was determined by potency ELISA. The peptides were synthesized to represent the motavizumab binding region on the antigenic site A of the full-length RSV F protein. F-peptide-10 was prepared with a terminal cysteine to facilitate coupling to a carrier protein in the event that the peptide could not be coated directly onto an ELISA plate.

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