Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus.

Title:

Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus.

identifier:	1804739
description:	epitope description:GLFGAIAGFIEGGW antigen name:Hemagglutinin host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	21078301

study type:	b cell assays
subject species:	Influenza A virus (A/New Caledonia/20/1999(H1N1))

fullName:	Anwar M Hashem Gary Van Domselaar Changgui Li Junzhi Wang Yi-Min She Terry D Cyr Jianhua Sui Runtao He Wayne A Marasco Xuguang Li

method:	biological activity

name:	Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus.
description:	The epitope sequcne is foudn in Chun S et al. Vaccine. 2008 Nov 11 26(48):6068-76 [PMID: 19007587]. Affinity-purified epitope-specific antibody was able to neutralize H5N1-pseudotype virus (a virus-like particle with HIV-1 expressing H5N1). The antibody inhibited syncytia formation.

name:	iedb
homePage:	http://www.iedb.org

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