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Title: Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice.
identifier: 1806474
description:
epitope description:PPQQPPQQPPQQPPQQ
antigen name:Circumsporozoite protein-related
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 20811151
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1021220
landingPage: http://www.iedb.org/assay/1806474
type:
Literature
publicationVenue:
J Clin Invest
dates:
2010
study type: b cell assays
subject species: Plasmodium yoelii
fullName:
Takayuki Shiratsuchi
Urvashi Rai
Anja Krause
Stefan Worgall
Moriya Tsuji
method:
ELISA
name:
Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice.
description:
Recombinant Ads expressing the (QGPGAP)3 peptide on the surface of the virus gave a weaker response to the epitope than Ads that only expressed the CS protein as a transgene. The response increased after multiple immunizations with the recombinant Ads.

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