Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1020198 |
| landingPage: |
http://www.iedb.org/assay/1808202 |
| type: |
Literature
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| publicationVenue: |
Immunol Lett
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| dates: |
1994
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| study type: | b cell assays |
| subject species: | Homo sapiens |
| fullName: |
A A Ghaderi
G Gaudernack
D R Stanworth
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| method: |
flow cytometry
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| name: |
Cross-linking of a sequential epitope within the beta-chain of HLA-DR/DP molecules suppressing B lymphocyte growth and inducing homotypic cell aggregation.
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| description: |
The deduced epitope is located in the ß
-chains of HLA-DR and HLA-DP.
The epitope was deduced based on sequence comparison of different HLA class II molecules that were found to react with the mAb to those of unreactive molecules. The epitope-specific mAb also bound to tonsillar B cells and induced cell aggregation and clumping.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
