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Title: Protection of BALB/c mice from respiratory syncytial virus infection by immunization with a synthetic peptide derived from the G glycoprotein.
identifier: 1808204
description:
epitope description:SICSNNPTCWAISK
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 1720589
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006803
landingPage: http://www.iedb.org/assay/1808204
type:
Literature
publicationVenue:
Virology
dates:
1991
study type: b cell assays
subject species:
fullName:
M
F Nadon
C Sé
guin
H Binz
method:
ELISA
name:
Protection of BALB/c mice from respiratory syncytial virus infection by immunization with a synthetic peptide derived from the G glycoprotein.
description:
The epitope sequence was provided in cited reference Sakate et al. Nucleic Acids Res 1985
13:7795 [PMID: 4069997]. The epitope was modified with a C186S substitution.
Mice immunized with the epitope conjugated to KLH produced virus-specific antibodies (1/1600) and were protected, but virus neutralizing titers were negligible.

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