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identifier: 1807909
description:
epitope description:alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')--N-acylsphingosine
host organism:Homo sapiens
antibody name:Do1
aggregation:
instance of dataset
availability:
available
primaryPublications: 9650753
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1018076
landingPage: http://www.iedb.org/assay/1807909
type:
Literature
publicationVenue:
Acta Neuropathol
dates:
1998
study type: b cell assays
subject species: Homo sapiens
fullName:
G M O'Hanlon
G J Paterson
J Veitch
G Wilson
H J Willison
method:
immuno staining
name:
Mapping immunoreactive epitopes in the human peripheral nervous system using human monoclonal anti-GM1 ganglioside antibodies.
description:
In solid-phase immunoassay, the antibody react with the epitope, and also to the structurally related glycolipids asialo-GM1 (GA1) and GD1b. The epitope-specific mAb was observed to bind to motor neurons and spinal grey matter, dorsal and ventral spinal roots, dorsal root ganglion neurons, nodes of Ranvier, neuromuscular junctions and skeletal muscle.

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