Abeta N-terminal-end specific antibody reduced beta-amyloid in Alzheimer-model mice. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Abeta N-terminal-end specific antibody reduced beta-amyloid in Alzheimer-model mice.

Dataset

identifier:	1807856
description:	epitope description:DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA antigen name:Amyloid beta A4 protein host organism:Mus musculus APPsw antibody name:82E1
aggregation:	instance of dataset
availability:	available
primaryPublications:	15530403

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1021123
landingPage:	http://www.iedb.org/assay/1807856

Publication

type:	Literature
publicationVenue:	Biochem Biophys Res Commun
dates:	2004

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	Yuko Horikoshi Takashi Mori Masahiro Maeda Noriaki Kinoshita Kumiko Sato Haruyasu Yamaguchi

Data Type

method:	ELISA

Study

name:	Abeta N-terminal-end specific antibody reduced beta-amyloid in Alzheimer-model mice.
description:	The epitope sequence is from the reference cited: Horikoshi et al. (2004) Biochem Biophys Res Commun 319(3):733-737 [PMID: 15184044]. Aß N-terminal-end specific mAb 82E1, which was raised against Aß 1-16, was used in conjunction with C-terminal-end specific Aß mAbs to quantitate the amount of insoluble epitope deposits found in the brain and plasma of Tg2576 mice.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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