Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1009140 |
| landingPage: |
http://www.iedb.org/assay/1809654 |
| type: |
Literature
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| publicationVenue: |
J Exp Med
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| dates: |
1986
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| study type: | b cell assays |
| subject species: | Streptococcus dysgalactiae subsp. equisimilis D181 |
| fullName: |
H M Fillit
M McCarty
M Blake
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| method: |
antigen inhibition
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| name: |
Induction of antibodies to hyaluronic acid by immunization of rabbits with encapsulated streptococci.
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| description: |
The epitope is stated to be the terminal glucuronic acid molecules in hyaluronic acid.
The epitope is the best inhibitor of the reactivity of the anti-encapsulated streptococcus antisera to hyaluronic acid. By analysis of the reactivity to other inhibitors and to modified hyaluronic acid, the carboxyl group of the terminal glucuronic acid of hyaluronate is suggested to be the primary focus of the immune response to hyaluronic acid in rabbits immunized with encapsulated streptococci.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
