Immunological Data Discovery Index
Advanced Search
identifier: 1812630
description:
epitope description:alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer
antigen name:lipooligosaccharide
host organism:Mus musculus C3H/He
antibody name:CGM3
aggregation:
instance of dataset
availability:
available
primaryPublications: 18184663
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1012585
landingPage: http://www.iedb.org/assay/1812630
type:
Literature
publicationVenue:
Brain
dates:
2008
study type: b cell assays
subject species: Campylobacter jejuni
fullName:
Susan K Halstead
Femke M P Zitman
Peter D Humphreys
Kay Greenshields
Jan J Verschuuren
Bart C Jacobs
Russell P Rother
Jaap J Plomp
Hugh J Willison
method:
immuno staining
name:
Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model.
description:
The epitope-specific mAb bound to mouse motor nerve terminals and disrupted their axonal integrity. Treatment of the cells with normal human serum showed complement binding, but the addition of another mAb, eculizumab directed against the complement protein C5, blocked complement deposition and protected axonal integrity..

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.