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Title: Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex.
identifier: 1812816
description:
epitope description:D-penicillamine
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 1378852
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1016124
landingPage: http://www.iedb.org/assay/1812816
type:
Literature
publicationVenue:
J Clin Invest
dates:
1992
study type: b cell assays
subject species:
fullName:
R L Rubin
S A Bell
R W Burlingame
method:
antigen inhibition
name:
Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex.
description:
Antibody from the patient reacted to DNA bound to H2A-H2B, a subunit of the nucleosome, as well as to denatured DNA. Adsorption of the antisera with DNA reduced binding to DNA.

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