Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi.

Title:

Dataset

identifier:	1811270
description:	epitope description:alpha-D-Galp-(1->6)-alpha-D-Galp-(1->3)-beta-D-Galf-(1->3)-alpha-D-Manp-(1->3)-alpha-D-Manp-(1->4)-alpha-D-GlcpN-(1->6)-myo-inositol antigen name:glycoinositol phospholipid host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7818483

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1019252
landingPage:	http://www.iedb.org/assay/1811270

Publication

type:	Literature
publicationVenue:	Biochem J
dates:	1994

Dimension

study type:	b cell assays
subject species:	Leishmania major

Person

fullName:	I C Almeida M A Ferguson S Schenkman L R Travassos

Data Type

method:	chromatography

Study

name:	Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi.
description:	The epitope is the glycan core of the glycoinositol phospholipid GIPL-3 of L. major. The GIPL-3 glycan core is found to be reactive with an anti-Gal antibody preparation from Chagasic patients in an affinity column.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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