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identifier: 1811759
description:
epitope description:alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group
antigen name:alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 7818483
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1019252
landingPage: http://www.iedb.org/assay/1811759
type:
Literature
publicationVenue:
Biochem J
dates:
1994
study type: b cell assays
subject species: Oryctolagus cuniculus
fullName:
I C Almeida
M A Ferguson
S Schenkman
L R Travassos
method:
chromatography
name:
Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi.
description:
The reference stated source molecule is ceramide pentahexoside from rabbit.
The anti-mammalian-alpha-Gal antibody preparation from Chagasic patient is found to react with the same structure but in the oxidized form from a mixture of galactose-oxidase-labelled oligosaccharides obtained from T. cruzi mucin-like glycoproteins.

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