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identifier: 1811764
description:
epitope description:alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc
antigen name:Variant surface glycoprotein (VSG, atypical), putative (UniProt:Q380X5)
host organism:Camelus dromedarius
antibody name:NbAn33-Tr-Apo-L-I
aggregation:
instance of dataset
availability:
available
primaryPublications: 16604085
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003946
landingPage: http://www.iedb.org/assay/1811764
type:
Literature
publicationVenue:
Nat Med
dates:
2006
study type: b cell assays
subject species: Trypanosoma brucei brucei
fullName:
Toya Nath Baral
Stefan Magez
Benoî
t Stijlemans
Katja Conrath
Benoit Vanhollebeke
Etienne Pays
Serge Muyldermans
Patrick De Baetselier
method:
immuno staining
name:
Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.
description:
This branched high-mannose oligosaccaride (Man9-GlcNAc2) is expressed at the Variable surface Glycoproteins (VSG) of T. brucei brucei and T. b. rhodesiense.
A construct of the epitope-specific camelid VHH fragment NbAn33 and the T. brucei-lytic enzyme apo-L-I is able to stain blood smears and cell suspensions of a T. b. brucei AnTat 1.1 infected mouse.

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