Carrier-specificity of a phosphorylcholine-binding antibody requires the presence of the constant domains and is not dependent on the unique VH49 glycine or VH30 threonine residues.

Title:

Carrier-specificity of a phosphorylcholine-binding antibody requires the presence of the constant domains and is not dependent on the unique VH49 glycine or VH30 threonine residues.

Dataset

identifier:	1811934
description:	epitope description:phosphocholine host organism:Mus musculus BALB/c antibody name:Mab2 Fab
aggregation:	instance of dataset
availability:	available
primaryPublications:	17331532

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1011337
landingPage:	http://www.iedb.org/assay/1811934

Publication

type:	Literature
publicationVenue:	J Immunol Methods
dates:	2007

Dimension

study type:	b cell assays
subject species:	Trichinella spiralis

Person

fullName:	Frankie C H Tam Chun Hung Ma Danny T M Leung Brian Sutton Pak-Leong Lim

Data Type

method:	ELISA

Study

name:	Carrier-specificity of a phosphorylcholine-binding antibody requires the presence of the constant domains and is not dependent on the unique VH49 glycine or VH30 threonine residues.
description:	The recombinant Fab fragment, and mutated forms of the recombinant Fv fragment (VH49 glycine and VH30 threonine) bound PC with comparable KDs. The Fv fragment of the epitope-specific mAb containing the [(gly4ser)3] linker bound more strongly.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.